I like the feel of the soil when I work in the garden and so no gloves for me. I need to however trim my nails which I unwillingly go for. I have always kept long nails and painted them too. Short nails are also useful while typing (lol)
What is important is that hands are thoroughly washed with soap after the work is done
I have been doing this for years and have had no issues with my health except that the hands do turn a bit rough for which I have a solution. I use aloe vera gel that is available in our garden, in plenty.
Do you use gloves while working in the garden?